Peptides for immunity and hormonal balance

• HCG (Human Chorionic Gonadotropin) 5000 IU – Glycoprotein hormone — 30,00 €
• KPV 10 mg – Tripeptide (Lys-Pro-Val) derived from α-MSH — 39,00 €
• Selank 5mg/10mg – Synthetic tuftsin analogue for research — 25,00 €
• Kisspeptin-10 5 mg/10 mg – Peptide regulator of the hormonal axis (GnRH stimulator) — 30,00 €
• Semax 5mg/10mg – ACTH(4-10) analogue neuropeptide for research — 30,00 €
• Thymosin Alpha-1 5 mg / 10mg – Thymic peptide (thymalfasin) — 30,00 €
• Thymulin 5mg/10mg – Zinc-dependent thymic nonapeptide for research — 30,00 €
• Gonadorelin Acetate 2 mg – GnRH agonist for laboratory research — 35,00 €
• Adamax 5 mg – Synthetic Semax analogue for research — 59,00 €
• Vilon 20 mg – Bioregulatory dipeptide (Lys-Glu) for research — 40,00 €
• LL-37 5 mg – Human cathelicidin (antimicrobial and immunomodulatory peptide) for wound, biofilm and innate immunity models — 60,00 €

Peptides for immunity and hormonal balance: the hypothalamic-pituitary axis, thymic peptides and neuroimmune regulation

The Peptology category “Peptides for immunity and hormonal balance” gathers molecules acting on three interconnected regulatory systems: the hypothalamic-pituitary-gonadal axis (kisspeptin, gonadorelin, HCG), thymic and immune regulation (thymosin alpha-1, thymulin, Vilon, KPV, LL-37) and the neuropeptide axis, which links the stress response to the immune response (Semax, Selank, Adamax).

All products ship with GLS in 3–5 working days — lyophilised, with confirmed purity above 99% (HPLC/MS) and an independent laboratory certificate (CoA) for every batch. More in the article Peptides: what they are, how they work and their safety profile.

The three axes of the category

Best-selling products in the category

Three molecules cover the most frequently studied scenarios — one per axis.

Comparison: the three levels of the hormonal axis

Kisspeptin-10, gonadorelin and HCG are often discussed together, yet they enter at three different points of the same cascade. That also determines what can be measured with each.

Which peptide for which research model?

• The highest level of the HPG axis: kisspeptin-10 acts through KISS1R on the GnRH neurons themselves — the molecule for models studying the regulation of the cascade rather than its end result.
• Pituitary response: gonadorelin is identical to natural GnRH and has a very short half-life — which is exactly why it is the classic tool for assessing the pulsatile pituitary response.
• Direct gonadal stimulation: HCG is a glycoprotein that binds the same receptor as LH and bypasses the two levels above it — the signal is longer, but the upstream axis remains unmeasured.
• T-lymphocyte maturation: thymosin alpha-1 is the best described thymic peptide — dendritic cells, TLR signalling, Th1 profile. Thymulin is a special case: its activity is zinc-dependent, and without a bound zinc ion the molecule is inactive.
• Peptide bioregulators: Vilon is the dipeptide Lys-Glu from the peptide bioregulator school — studied for its influence on gene expression in thymic and lymphoid cell models, that is, at an entirely different level from the hormonal peptides.
• Inflammation control: KPV is the C-terminal tripeptide of α-MSH (Lys-Pro-Val) — it retains the anti-inflammatory part of α-MSH's action without the melanocortin effects. It is studied mainly in relation to NF-κB and the intestinal barrier.
• Innate immunity and antimicrobial peptides: LL-37 is the only human cathelicidin — an amphipathic 37-amino-acid peptide with a dual role: it interacts with bacterial membranes in models of antimicrobial action and regulates the inflammatory response (chemotaxis, TLR signalling). It is also studied in skin biology, as part of the first barrier of defence.
• Neurotrophic and cognitive models: Semax is the standard in BDNF/NGF models, while Adamax is a more recent modification of the same family with a different stability profile.
• Anxiety and the neuroimmune link: Selank is a tuftsin analogue — an immunopeptide whose anxiolytic effects in models go hand in hand with measurable changes in the cytokine profile, IL-6 included.

Combinations of products from the category

The logic is the same everywhere: you combine molecules that act on different receptors or different levels of the same process. Molecules of the same receptor class merely compete with one another.

Conversely, Semax together with Adamax adds no information: both derive from the same ACTH fragment and compete for the same targets. Likewise, gonadorelin and HCG used together make the model unreadable — HCG bypasses the pituitary and masks precisely the signal gonadorelin is meant to measure.

Storage and safety rules

In lyophilised form the products are stored at 2–8 °C, protected from direct light and moisture. Glycoproteins (HCG) and longer peptide chains such as thymosin alpha-1 are more sensitive to temperature fluctuations than short peptides — for these, refrigeration immediately after reconstitution is recommended, along with avoiding repeated warming cycles.

• After reconstitution with Peptide Matrix Water™ — stable for up to 60 days at +2 °C to +8 °C.
• After reconstitution with bacteriostatic water — up to 28 days under the same conditions. Do not refreeze a solution that has already been reconstituted. The differences between the solvents are explained in this article.
• Direct the solvent slowly down the inner wall of the vial. Swirl gently, never shake — mechanical stress destroys peptide structure, and with glycoproteins such as HCG the risk is greater still.
• For an exact calculation of volume and concentration use the peptide calculator.
• Disinfect the rubber stopper with an alcohol swab before every withdrawal and note the date of first puncture on the label.

Important notice: The products in this category are intended exclusively for laboratory research and scientific in-vitro analysis. They are not medicines, not approved preparations and not suitable for use in humans or animals. The mechanisms described come from the published scientific literature and constitute neither a promise of effect, nor a recommendation for use, nor a claim about the action of the research-grade products offered.