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Adamax
Adamax 5 mg – Synthetic Semax analogue for research
Peptology Ltd. · Peptides for immunity and hormonal balance
Adamax 5 mg – nootropic peptide for research on cognitive support and neuroprotection. Described as a modified analogue of Semax with an added adamantane group for improved CNS stability; primary research focus – BDNF/TrkB. Purity over 99 %. For research use only.
📦 The product is in our EU warehouse – delivery within 3–5 working days.
59,00 € · In stock
For research use only / Not a medicine
| Purity | 99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
What is Adamax?
Adamax is a research nootropic peptide, described by vendors as a modified analog of Semax — a neuropeptide from the ACTH(4-10) family. According to available descriptions, an adamantane group has been added to the Semax structure with the aim of improving blood–brain barrier penetration, enzymatic and thermal stability, and duration of action.
The family to which Adamax belongs is investigated in the context of cognitive support, memory, focus and neuroprotection. These directions are based mainly on the broader Semax literature, which reports effects on BDNF, neuroplasticity and neuroprotection in Russian scientific publications.
Transparency note: There is no primary peer‑reviewed literature for "Adamax" as a clearly defined compound. Available sources are vendor‑level and sometimes contradictory (some conflate it with the peptide "P21"). Therefore we present Adamax as a Semax‑derived analog and direct mechanistic data to the established Semax literature. The properties below should be interpreted cautiously.
In the Peptology version Adamax is supplied as a lyophilized research peptide with purity over 99%, confirmed by independent laboratory analysis (see the product certificates). The product is intended for research use only and is not a medicinal product. See related nootropic peptides Semax and Selank in the Peptides for immunity and hormonal balance category.
How Adamax is studied — mechanism (by analogy with Semax)
Because Adamax is described as an analog of Semax, expected mechanisms are extrapolated from that family. The three axes below summarize the main directions in which Semax‑like peptides are studied.
BDNF / TrkB
This class is studied for increasing BDNF and sensitization of the TrkB receptor — key elements for neuroplasticity and memory formation.
NEUROMEDIATORS
Modulation of dopamine, noradrenaline and serotonin is investigated in the context of cognition, attention and focus.
NEUROPROTECTION
Antioxidant and anti‑inflammatory aspects are examined for neuroprotection in Semax models.
The role of BDNF in cognition
BDNF (brain‑derived neurotrophic factor) is central to neuron survival, synaptic plasticity and memory formation. In the literature Semax is associated with increases in BDNF and its receptor TrkB — a mechanism considered fundamental to the cognitive and neuroprotective effects of the family. By analogy, this axis is a focus when studying Semax‑like compounds such as Adamax.
Why the adamantane modification
Adamantane is a bulky, lipophilic moiety often added to molecules to increase stability and membrane permeability, including blood–brain barrier penetration. According to vendor descriptions this modification distinguishes Adamax from parent Semax — the intent being improved CNS bioavailability and longer duration. We emphasize this claim originates from vendor sources, not peer‑reviewed data.
The nootropic peptide family
Nootropic peptides are short amino‑acid chains studied for support of cognitive functions and the resilience of the nervous system to stress. Among the most investigated are Semax (cognitive / neuroprotective profile) and Selank (anxiolytic profile). Adamax is positioned in this group as a Semax‑derived analog aimed at cognition and focus.
COGNITION
Memory, learning, concentration — the main focus of the Semax family.
FOCUS
Attention and mental clarity via modulation of neuromediators.
PROTECTION
Neuroprotection against oxidative and ischemic stress in models.
Properties and characteristics
- Type: nootropic peptide, described as a Semax‑derived analog
- Family: ACTH(4-10) / Semax‑like peptides
- Described modification: added adamantane group for stability and CNS bioavailability (vendor data)
- Quantity: 5 mg per vial, lyophilized powder
- Purity: over 99%, with CoA for each batch
- Typical form: small vials, characteristic for intranasal/subcutaneous nootropic peptides in research contexts
- Application: research use only (in vitro / laboratory models)
Adamax vs Semax and Selank
The table compares Adamax with the two most studied nootropic peptides. Since Adamax lacks primary literature, the listed properties are based on the Semax family and should be interpreted cautiously.
| Adamax | Semax | Selank | |
|---|---|---|---|
| Family | Semax‑analog | ACTH(4-10) | Tuftsin |
| Profile | Cognition / focus | Cognition | Anxiolytic |
| Primary axis | BDNF / TrkB | BDNF / TrkB | GABA / serotonin |
| Data base | Very limited | More extensive (RU) | More extensive (RU) |
The comparison is indicative and for scientific reference. It does not constitute a claim of comparative efficacy — data for Adamax are vendor‑derived and limited.
Scientific basis and availability of data
Literature on Semax
Parent Semax has a real scientific basis, mainly in Russian publications linking it to increased BDNF, neuroprotection in ischemia and support of cognitive functions. Because Adamax is described as its analog, this literature is the closest available reference for expected mechanisms.
Lack of Adamax‑specific data
No specific clinical or animal studies for the compound "Adamax" were found in peer‑reviewed databases. Its descriptions originate from vendor sources that sometimes contradict each other — for example by conflating it with the peptide P21, which is mechanistically distinct. This requires cautious interpretation of any efficacy claims.
Due to the limited and sometimes contradictory documentation, all information here is indicative, based on the Semax family, and is for scientific reference only — not a claim of effect or a recommendation for use.
Research dosing protocols
Important: Due to the lack of defined data for Adamax there is no established protocol. Small vials (5 mg) are typical for intranasal/subcutaneous nootropic peptides in research contexts. The information is for scientific reference only, not a recommendation for individual use, medical advice or instructions for application.
- Lyophilized; reconstitute with a stabilizing solution according to protocol.
- Nootropic peptides from the Semax family are typically studied in intranasal or subcutaneous form.
- Specific concentration is determined by reconstitution volume and research objectives.
Documented research focus
- Cognitive support — memory, learning and concentration (by analogy with Semax).
- Focus and attention — modulation of dopamine, noradrenaline and serotonin.
- Neuroprotection — antioxidant and anti‑inflammatory aspects in Semax models.
- Neuroplasticity — the BDNF/TrkB axis as a primary research interest.
The indicated directions are based on the Semax family and do not constitute a claim of Adamax's effect or a recommendation for use.
Storage and reconstitution
- Before reconstitution: lyophilized, frozen (−20 °C), protected from light and moisture.
- After reconstitution: refrigerate 2–8 °C; do not refreeze.
- Reconstitution: add the solvent slowly down the vial wall; swirl gently, do not shake.
Lab tip: for reconstitution Peptide Matrix Water™ — a stabilizing solution for reconstituted research peptides. Alternatively you can add bacteriostatic water to your order.
Frequently asked questions about Adamax
Is Adamax the same as Semax?
No, but it is described as its modified analog. The exact structure is not confirmed in peer‑reviewed literature, so mechanistic data refer to Semax.
Are there clinical studies for Adamax?
No specific clinical or animal studies for Adamax were found. This is a research compound with limited documentation.
What is the difference compared to P21?
Some sources conflate Adamax with P21, but the two peptides are described as mechanistically distinct. Due to contradictory data we recommend cautious interpretation.
What should it be reconstituted with?
We recommend Peptide Matrix Water™ or bacteriostatic water. After reconstitution store refrigerated and do not refreeze.
Is a prescription required?
No. It is offered for research purposes and does not require a prescription.
Related products
Semax
Nootropic neuropeptide
Selank
Anxiolytic nootropic
Peptide Matrix Water™
Stabilizing solution for reconstitution
See the full catalog: Peptides for immunity and hormonal balance · Peptide research blog
Research warning: Adamax is supplied for research purposes and in vitro applications only. The product is not approved for clinical use, is not a medicinal product and is not intended for administration to humans or animals. Due to the limited and sometimes contradictory available literature the information presented is indicative, based on the Semax family, and is for scientific reference only. It does not constitute medical advice, instructions for application or a recommendation for use. Before starting any research consult a qualified specialist and the applicable regulatory framework. Peptology is not responsible for unauthorized use of research peptides.
Laboratory reconstitution
Laboratory protocol — reconstitution, research protocols, storage
Standardized protocol applicable to all research peptides in the Peptology catalogue. To calculate the solution concentration (mg/mL) for each vial, use the peptide reconstitution calculator.
60-second protocol
1. SOLVENT
2. RECONSTITUTION
Add the solvent down the side of the vial, without shaking, wait 10–15 min.
3. CALCULATION
Calculator → concentration mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilized powder |
| Solvent | Peptide Matrix Water |
| Reconstitution volume | 1–3 mL — maximum 3 mL (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration not required) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you need
Precision pipette
Calibrated, 100–1000 µL — for accurately measuring the volume of solvent added to the vial.
70% alcohol swabs
Two swabs — to disinfect the peptide vial and the solvent vial.
Stabilized solvent for lyophilized peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Mistake |
|---|---|
| Disinfect the vial caps and the work surface with 70% alcohol; wear gloves | Working without disinfection |
| Add the solvent slowly along the vial wall | Direct jet onto the powder — foaming and denaturation |
| Gentle rolling between the palms | Shaking — foam, which denatures peptides |
| 10–15 minutes waiting at room temperature | Mechanical mixing or heating |
| Visual check: clear, particle-free | Working with a cloudy or discolored solution |
Calculating concentration
⚠️ Maximum 3 mL solvent. The standard vial does not accommodate larger volumes — do not exceed during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after adding the solvent (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 5 mg | 5 mg/mL | 2.5 mg/mL | 1.67 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in original packaging. Refrigerator not required.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard any remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade peptide structure.
Four mistakes to avoid
1. Shaking "to dissolve faster"
Foam = denaturation. Only gentle rolling between the palms.
2. Inappropriate solvent
For peptide stability use only sterile, specially formulated solvent — recommended Peptide Matrix Water.
3. Ignoring slight turbidity
Not fully clear = the sample does not meet the criteria for use.
4. Taking it out of the refrigerator "for an hour–two"
Short exposures add up and compromise stability.
Research status: All Peptology products are intended for laboratory and research use only. They are not medicinal products, not approved for human or veterinary use and do not substitute medical advice. The described protocol is standard laboratory practice for working with lyophilized peptides.
Shipping information
🚚 Shipping information
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Products in our warehouse – orders placed by 15:00 on working days are dispatched the same day, later orders on the next working day.
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Delivery with GLS to your address in 3–5 working days.
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Shipping costs €5 and is free from €50.
Frequently Asked Questions (FAQ)
Is Adamax the same as Semax?
No, but it has been described as its modified analogue with an added adamantane group. The exact structure has not been confirmed in peer-reviewed literature, so mechanistic data refer to Semax.
What is Adamax being investigated for?
In the context of cognitive support, memory, focus and neuroprotection — by analogy with the broader literature on Semax and the BDNF/TrkB pathway.
Are there clinical studies for Adamax?
No. No clinical or animal studies specific to Adamax have been identified. This is a research compound with limited and sometimes conflicting documentation.
How does it differ from P21?
Some sources conflate Adamax with the peptide P21, but the two are described as mechanistically distinct. Due to conflicting data we recommend cautious interpretation.
How should it be reconstituted and stored?
We recommend Peptide Matrix Water™ or bacteriostatic water. Lyophilised – frozen at −20 °C; after reconstitution refrigerated at 2–8 °C, do not refreeze.
Is a prescription required?
No. Supplied for research purposes, no prescription required.
Where can I buy Adamax in Europe and what does it cost?
You can buy Adamax in Europe online from Peptology, from 59,00 €. Delivery with GLS in 3–5 working days. Shipping is free from 50,00 €. Payment by card. Purity 99%+, with an HPLC report for every batch.
Laboratory Analysis
Adamax - 5mg - Batch - 0226 - Purity
