🇪🇺 Fast delivery (3–5 working days) with GLS ✅ Card or bank transfer 📦 Free shipping from €50
Thymosin Alpha-1
Thymosin Alpha-1 5 mg / 10mg – Thymic peptide (thymalfasin)
Peptology Ltd. · Peptides for immunity and hormonal balance
Thymosin Alpha‑1 5 mg (thymalfasin) – an N-terminally acetylated, 28-amino-acid synthetic thymic peptide derived from prothymosin α; research peptide for T-cell and NK-cell immune models. Purity 99%+, HPLC/MS report for every batch.
📦 The product is in our EU warehouse – delivery within 3–5 working days.
30,00 € · In stock
- 5mg — 30,00 €
- 10mg — 45,00 €
For research use only / Not a medicine
| Purity | >99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
Last updated: 18/10/2026
What is Thymosin Alpha-1 5 mg / 10 mg?
Thymosin Alpha-1 (thymalfasin) is a synthetic thymic peptide composed of 28 amino acids — one of the most potent studied immunostimulating peptides. In the research literature it is associated with the activation of T lymphocytes and NK cells, strengthening of cellular immunity, cytokine modulation, and support of the antiviral and antitumor response.
Thymosin Alpha-1 belongs to the category peptides for immunity and hormonal balance. It is one of the three "immune" peptides in the catalog, alongside the related thymic peptide Thymulin and the anti-inflammatory KPV.
Important distinction: Thymalfasin has been studied clinically (including in viral hepatitis B and C and as immune support). The product offered by Peptology is a research-grade reagent — it is not a medicinal product and does not serve to treat infections or diseases.
In the version offered by Peptology, Thymosin Alpha-1 is available in two dosage variants — 5 mg and 10 mg — as a lyophilized peptide of high purity, confirmed by independent laboratory analysis (CoA for every batch). The product is intended exclusively for scientific research and in vitro applications.
How Thymosin Alpha-1 works — the immunostimulating mechanism
In the research literature, Thymosin Alpha-1 is described as a peptide that "fine-tunes" cellular immunity. Below are the three most frequently studied elements.
T AND NK CELLS
Activates the T lymphocyte response and stimulates NK cells (natural killers) — including antitumor activity.
ANTIVIRAL RESPONSE
Strengthens the antiviral response and the reaction to vaccines (studies on HBV, HCV, HPV, HIV, influenza).
CYTOKINE MODULATION
Regulates inflammation through cytokine modulation; supports recovery after infections and therapies.
Why it is a "potent immunostimulator"
Thymosin Alpha-1 is one of the best clinically studied thymic peptides — as thymalfasin it was studied in chronic viral infections, in oncology patients (lower frequency of infections during chemotherapy) and in the context of the response to vaccination. It acts as an active immunostimulator (stimulates cellular immunity), in contrast to the more "regulatory" Thymulin or the purely anti-inflammatory KPV.
It is also worth distinguishing it from Thymosin Beta-4 (and its fragment TB-500): Alpha-1 modulates immunity, while Beta-4 supports tissue repair. This data comes from studies on thymalfasin and does not constitute a claim about the effect of the research-grade product offered by Peptology.
Pharmacokinetics and pharmacodynamics (research framework)
Thymosin Alpha-1 is a 28-amino-acid thymic peptide with a good tolerability profile. The most important research characteristics:
- Class: thymic peptide (28 aa), thymalfasin — immunostimulator
- Targets: activation of T and NK cells, cytokine modulation, antiviral response
- Research status: thymalfasin has been studied in clinical trials
- Tolerability profile: good even at high doses in published studies
- Schedule: subcutaneous administration is described, usually 1–2 times a week or per protocol
- Route of administration in protocols: subcutaneous, per the research protocol
Variant comparison: Thymosin Alpha-1 5 mg vs 10 mg
Thymosin Alpha-1 is available in two doses. Both variants are the same peptide — the difference concerns only the amount of substance in the vial, which translates into the scale and length of the research protocol.
| Thymosin Alpha-1 5 mg | Thymosin Alpha-1 10 mg | |
|---|---|---|
| Amount of peptide | 5 mg | 10 mg |
| Peptide | Thymosin Alpha-1 (28 aa) | Thymosin Alpha-1 (28 aa) |
| Purity | High (CoA per batch) | High (CoA per batch) |
| Protocol scale | Smaller / shorter | Larger / longer |
| Best for | Initial / shorter research series | Extended protocols / economy of scale |
Both variants are the same high-purity peptide — the difference concerns only the amount in the vial. The choice depends on the scale of the planned protocol. Regardless of the variant, it is worth adding Peptide Matrix Water™ for reconstitution.
Comparison: Thymosin Alpha-1 vs Thymulin vs KPV
Within the same category, it is worth comparing Thymosin Alpha-1 with two other immune peptides — the related thymic peptide Thymulin and the anti-inflammatory KPV. All concern immunity, but via different pathways.
| Thymosin Alpha-1 (this page) | Thymulin | KPV | |
|---|---|---|---|
| Origin | Thymic peptide (28 aa) | Thymic hormone (nonapeptide, FTS) | Tripeptide (fragment of α-MSH) |
| Main mechanism | Activation of T and NK cells | T-cell maturation (zinc-dependent) | Anti-inflammatory action |
| Profile | Potent immunostimulator | Neuroimmune regulator | Dampening of inflammation |
| Dose (variants) | 5 / 10 mg | 5 / 10 mg | 10 mg |
| Best for research on | Immune stimulation, viral infections | Neuroimmune-hormonal balance | Dampening inflammation, the gut |
Thymosin Alpha-1 strongly stimulates immunity (T/NK cells), Thymulin regulates the neuroimmune axis (zinc-dependent), and KPV dampens inflammation. In studies they are sometimes presented as complementary. The comparison is indicative in nature and does not constitute a recommendation for use.
Research data on Thymosin Alpha-1
Thymosin Alpha-1 (thymalfasin) is among the best clinically studied thymic peptides. Below are the most important directions — they concern the molecule/drug, not the research-grade product.
Viral infections and immunity
In clinical studies, thymalfasin was associated with improved elimination of viruses (including HBV, HCV, HPV, HIV) and enhancement of the response to antiviral vaccines.
Oncology and support after therapies
In oncology patients, a reduced frequency of infections during chemotherapy was observed (activation of NK cells, antitumor action), as well as better recovery after illness. It is also studied in the context of respiratory tract infections.
Safety profile
Thymalfasin is described as well tolerated even at high doses, without serious side effects at therapeutic doses. This is data on the drug/molecule, not a claim about the research-grade product.
Note: The information is presented for scientific and informational purposes and is based on the literature on thymalfasin. It does not constitute medical advice, a recommendation for use or a claim about the effect of the research-grade product offered by Peptology.
Thymosin Alpha-1 profile at a glance
- Thymic peptide (28 aa, thymalfasin) — one of the most potent studied immunostimulators
- Activates T and NK cells — cellular immunity, antitumor action (studies)
- Strengthens the antiviral response and the reaction to vaccination
- Studied clinically as thymalfasin — but the research-grade product is not a medication
- Other immune peptides: Thymulin (regulator) and KPV (anti-inflammatory)
- Every batch with a CoA and confirmed laboratory purity
All information provided refers to the research literature on Thymosin Alpha-1 / thymalfasin and should not be interpreted as a promise of effect, an instruction for use or a claim about the effect of the research-grade product offered by Peptology.
Research dosing protocols
Important: The information below describes schedules used in research on Thymosin Alpha-1. It is provided for scientific and informational purposes and does not constitute a recommendation for individual use, medical advice or administration instructions. The research-grade Thymosin Alpha-1 offered by Peptology is not a registered drug.
In research protocols, Thymosin Alpha-1 is usually administered after reconstitution of the lyophilizate, most often subcutaneously:
- Subcutaneous administration is described, usually 1–2 times a week or per protocol
- The 5 mg variant for initial, shorter series; 10 mg for extended protocols
- Calculate precise volumes and units in the peptide calculator (max. 3 mL of solvent per vial)
- In regenerative research it is sometimes paired with TB-500, BPC-157 or Semax
These schedules come from the research literature and do not constitute a recommendation for self-administration.
Side effects and safety
In studies, Thymosin Alpha-1 is described as well tolerated, even with prolonged use. Side effects are rare and mild. The data concern research on the molecule/drug.
Rare (mild)
- Redness or pain at the injection site
- Fatigue, headache or dizziness
Very rarely
- Chills or fever
Tolerability profile
- Good tolerability even at high doses
- No serious effects at therapeutic doses
- Hypersensitivity to components — to consider
At therapeutic doses, no serious side effects were observed in studies. This information is scientific in nature and does not constitute an instruction for use.
Storage and reconstitution
Thymosin Alpha-1 is supplied as a lyophilized (freeze-dried) powder in a vial. In lyophilized form it is stable at room temperature, protected from light and moisture — refrigeration before reconstitution is not mandatory. After reconstitution, stability depends on the solvent used, with Peptide Matrix Water™ significantly extending the peptide's lifespan.
- Before reconstitution: room temperature, in the original packaging, protected from light and moisture. A refrigerator is not mandatory.
- After reconstitution with Peptide Matrix Water™: stability in the refrigerator +2 °C to +8 °C for up to 60 days under appropriate laboratory conditions — the stabilizing formula extends the peptide's lifespan relative to standard solvents.
- After reconstitution with bacteriostatic or sterile water: stability in the refrigerator +2 °C to +8 °C for up to 28 days under appropriate conditions. Do not refreeze the reconstituted solution.
- Reconstitution: in a laboratory setting, Peptide Matrix Water™, bacteriostatic water or sterile water for injection is usually used, depending on the protocol.
- Volume: maximum 3 mL of solvent (capacity of a standard vial). For a precise calculation of volume and units, use the peptide calculator.
- Homogenization: add the solvent slowly down the vial wall, without vigorous shaking, then wait 10–15 min. Swirl gently, do not shake.
Laboratory tip: With your order, you can add Peptide Matrix Water™ to the cart — a stabilizing solution designed for working with reconstituted research peptides. More in the article Bacteriostatic water vs acetic acid vs matrix water.
Frequently asked questions about Thymosin Alpha-1
What exactly is Thymosin Alpha-1?
It is a synthetic thymic peptide composed of 28 amino acids (thymalfasin), a potent immunostimulator. In studies it is associated with the activation of T and NK cells, strengthening of immunity and the antiviral response. The results come from the research and clinical literature.
Is it a medicine?
No. The product offered by Peptology is a research-grade reagent, not a drug.
How does it differ from Thymosin Beta-4 / TB-500?
Alpha-1 modulates and stimulates immunity (T/NK cells), while Beta-4 (and its fragment TB-500) supports tissue repair and dampens inflammation. These are two different peptides with different research applications.
How does it differ from Thymulin?
Both are thymic peptides, but different molecules. Thymosin Alpha-1 strongly stimulates T/NK cells (immunostimulation), while Thymulin (zinc-dependent) more so regulates T-cell maturation and the neuroimmune axis.
How is Thymosin Alpha-1 stored and reconstituted?
The lyophilized vial is stored at room temperature, protected from light and moisture. After reconstitution, stability depends on the solvent: with Peptide Matrix Water™ — up to 60 days in the refrigerator +2 °C to +8 °C; with bacteriostatic or sterile water — up to 28 days. Avoid refreezing.
Where to buy Thymosin Alpha-1 for research?
Peptology offers Thymosin Alpha-1 (5 mg / 10 mg) as a research peptide with confirmed purity and independent laboratory analysis for every batch. Fast shipping, discreet packaging and certificates of purity with the product. For scientific background, also see the article Peptides — what they are, how they work, main categories and safety profile.
Related products in the Peptology catalog
Researchers working with Thymosin Alpha-1 often also consider related peptides of immunity, the hormonal axis and regeneration. Each of the products below has a certificate of purity (CoA):
Thymulin
Thymic peptide — neuroimmune regulator (Zn)
KPV
Anti-inflammatory peptide — immunity and the gut
TB-500 (Thymosin β4)
Tissue repair (a contrast with Alpha-1)
Kisspeptin-10
Regulator of the hormonal axis (GnRH)
Semax
Neuropeptide — neuroendocrine adaptation
Peptide Matrix Water™
Stabilizing solution for reconstitution
See the full catalog: Peptides for immunity and hormonal balance · Peptides for energy and regeneration · Recovery and anabolic peptides · All peptides · Blog on peptide research
Research warning: Thymosin Alpha-1 is offered exclusively for scientific research and in vitro purposes. It is not a medicinal product, is not approved for use in humans or animals, and does not replace medical advice. All information comes from the research literature and is provided for scientific and informational purposes; it does not constitute a claim about the effect of the product.
Molecule identity
| CAS number | 62304-98-7 |
|---|---|
| Molecular weight | 3108.3 g/mol |
| Molecular formula | C129H215N33O55 |
| Class | Thymic peptide (28 amino acids) |
| Form | Lyophilised powder in a glass vial |
| Storage | Lyophilisate: 2–8 °C, dry and protected from light · after reconstitution: 2–8 °C |
Laboratory reconstitution
Laboratory protocol — reconstitution, research protocols, storage
Standardized protocol applicable to all research peptides in the Peptology catalogue. To calculate the solution concentration (mg/mL) for each vial, use the peptide reconstitution calculator.
60-second protocol
1. SOLVENT
2. RECONSTITUTION
Add the solvent down the side of the vial, without shaking, wait 10–15 min.
3. CALCULATION
Calculator → concentration mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilized powder |
| Solvent | Peptide Matrix Water |
| Reconstitution volume | 1–3 mL — maximum 3 mL (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration not required) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you need
Precision pipette
Calibrated, 100–1000 µL — for accurately measuring the volume of solvent added to the vial.
70% alcohol swabs
Two swabs — to disinfect the peptide vial and the solvent vial.
Stabilized solvent for lyophilized peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Mistake |
|---|---|
| Disinfect the vial caps and the work surface with 70% alcohol; wear gloves | Working without disinfection |
| Add the solvent slowly along the vial wall | Direct jet onto the powder — foaming and denaturation |
| Gentle rolling between the palms | Shaking — foam, which denatures peptides |
| 10–15 minutes waiting at room temperature | Mechanical mixing or heating |
| Visual check: clear, particle-free | Working with a cloudy or discolored solution |
Calculating concentration
⚠️ Maximum 3 mL solvent. The standard vial does not accommodate larger volumes — do not exceed during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after adding the solvent (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 5 mg | 5 mg/mL | 2.5 mg/mL | 1.67 mg/mL |
| 10 mg | 10 mg/mL | 5 mg/mL | 3.33 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in original packaging. Refrigerator not required.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard any remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade peptide structure.
Four mistakes to avoid
1. Shaking "to dissolve faster"
Foam = denaturation. Only gentle rolling between the palms.
2. Inappropriate solvent
For peptide stability use only sterile, specially formulated solvent — recommended Peptide Matrix Water.
3. Ignoring slight turbidity
Not fully clear = the sample does not meet the criteria for use.
4. Taking it out of the refrigerator "for an hour–two"
Short exposures add up and compromise stability.
Research status: All Peptology products are intended for laboratory and research use only. They are not medicinal products, not approved for human or veterinary use and do not substitute medical advice. The described protocol is standard laboratory practice for working with lyophilized peptides.
Shipping information
🚚 Shipping information
-
Products in our warehouse – orders placed by 15:00 on working days are dispatched the same day, later orders on the next working day.
-
Delivery with GLS to your address in 3–5 working days.
-
Shipping costs €5 and is free from €50.
Frequently Asked Questions (FAQ)
What is the difference between Thymosin Alpha-1 and Thymosin Beta-4?
Alpha-1 modulates the immune system, while Beta-4 supports tissue repair and reduces inflammation.
In what form is Thymosin Alpha-1 supplied and how should it be stored?
It is supplied as a lyophilized (freeze-dried) powder in a sealed vial. Store the unopened vial dry and protected from light, ideally at 2–8 °C. After laboratory reconstitution, keep the solution at 2–8 °C and use it within the period stated in the “Laboratory reconstitution” tab (up to 60 days with Peptide Matrix Water).
Is a prescription required to order?
No – the product is for laboratory and research use only.
Where can I buy Thymosin Alpha-1 in Europe and what does it cost?
You can buy Thymosin Alpha-1 in Europe online from Peptology, from 30,00 €. Delivery with GLS in 3–5 working days. Shipping is free from 50,00 €. Payment by card. Purity 99%+, with an HPLC report for every batch.
Laboratory Analysis
Thymosin Alpha‑1 - 5mg - Batch - 0226 - Purity
Thymosin Alpha‑1 - 10mg - Batch - 0226 - Purity
