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Selank
Selank 5mg/10mg – Synthetic tuftsin analogue for research
Peptology Ltd. · Peptides for immunity and hormonal balance
Selank 5 mg – a synthetic heptapeptide analogue of tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro sequence at the C-terminus; a nootropic and anxiolytic research peptide studied in Russia. Purity 99%+, HPLC/MS report for every batch.
📦 The product is in our EU warehouse – delivery within 3–5 working days.
25,00 € · In stock
- 5mg — 25,00 €
- 10mg — 35,00 €
For research use only / Not a medicine
| Purity | >99% |
|---|---|
| Method | HPLC + LC/MS |
| Laboratory | Analiza Białek |
| Batch | 0226 |
What is Selank 5 mg?
Selank is a synthetic nootropic and anti-anxiety (anxiolytic) peptide, a derivative of the natural immune tetrapeptide tuftsin. In the research literature it is associated with the reduction of anxiety and stress, improvement of concentration, memory and learning, and additional immunomodulatory action.
Selank belongs to the category peptides for immunity and hormonal balance, in which compounds linking the nervous, immune and hormonal systems are studied. Together with the related Semax, it forms the classic "nootropic pair" studied in Russia.
In short: Selank is a "calming and sharpening" peptide — in studies it reduces tension and anxiety, while at the same time supporting cognitive functions, without the sedation typical of classic anxiolytics.
In the version offered by Peptology, Selank is available in the 5 mg variant as a lyophilized peptide of high purity, confirmed by independent laboratory analysis (CoA for every batch). The product is intended exclusively for scientific research and in vitro applications.
Variant: Selank 5 mg
Selank is offered in one variant — a vial containing 5 mg of lyophilized peptide. This is a standard amount for nootropic research protocols.
VIAL CONTENTS
5 mg of lyophilized Selank of high purity, CoA for the batch.
PROFILE
Heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro (tuftsin analogue).
RECONSTITUTION
Max. 3 mL solvent; Peptide Matrix Water™ is recommended.
How Selank works — the neuropsychotropic mechanism
In the research literature, Selank acts on the central nervous system through multiple channels. Below are the three most frequently studied elements.
GABA SYSTEM
Modulates GABAergic transmission, strengthening the anti-anxiety and calming action.
NEUROTRANSMITTERS
Regulates serotonin and dopamine levels and BDNF expression — affecting mood and cognition.
IMMUNOMODULATION
As a tuftsin derivative it supports immune functions — linking the neural and immune axes.
Why it is an "anxiolytic-nootropic" peptide
Selank stands out because it combines a calming effect with improved cognitive function — in contrast to classic anti-anxiety drugs, no sedation is described. As a tuftsin derivative it additionally modulates immunity, which places it at the interface of the nervous and immune systems. This distinguishes it from the more "activating" and neuroprotective Semax, with which it is sometimes combined in studies for a synergistic effect.
This data comes from the research literature (mainly Russian) and does not constitute a claim about the effect of the research-grade product offered by Peptology.
Pharmacokinetics and pharmacodynamics (research framework)
Selank is a short peptide (heptapeptide). The most important research characteristics:
- Class: synthetic peptide (tuftsin derivative) — anxiolytic + nootropic + immunomodulator
- Targets: the GABA system, serotonin/dopamine, BDNF, the neuroimmune axis
- Onset of action: described as fast — first effects within a few days
- Schedule: subcutaneous or intranasal administration is described, per the protocol
- Synergy: in studies often paired with Semax (the nootropic pair)
Comparison: Selank vs Semax vs Thymulin
Within the same category, it is worth comparing Selank with two other neuroimmune peptides — the nootropic Semax and the neuroimmune-axis-regulating Thymulin. All link the nervous system with the immune system, but with an emphasis on different effects.
| Selank (this page) | Semax | Thymulin | |
|---|---|---|---|
| Origin | Tuftsin derivative (peptide) | ACTH fragment (peptide) | Thymic hormone (nonapeptide) |
| Main action | Anti-anxiety + nootropic | Nootropic + neuroprotective | Neuroimmune regulation |
| Main target | GABA, serotonin/dopamine | BDNF, dopamine, neuroprotection | T-cell maturation (Zn) |
| Profile | Calming | Activating, stimulating | Immune-regulating |
| Best for research on | Anxiety, stress, concentration | Memory, neuroprotection | Neuroimmune-hormonal balance |
Selank calms anxiety and supports concentration, Semax is more activating and protects neurons, and Thymulin regulates the neuroimmune axis. Selank and Semax are sometimes combined as a complementary nootropic pair. The comparison is indicative in nature and does not constitute a recommendation for use.
Research data on Selank
Selank was developed and studied mainly in Russia as a peptide anxiolytic. Below are the most important directions — they concern the molecule, not the research-grade product.
Anxiety and stress
In studies, Selank was associated with a significant reduction in anxiety and tension and stabilization of the psycho-emotional state — without the sedation typical of classic benzodiazepine anxiolytics.
Cognitive functions
Improvement in concentration, memory and learning ability was observed, as well as an increase in "mental energy". The effects were associated, among other things, with the regulation of neurotransmitters and BDNF expression.
Immunomodulation
As a tuftsin derivative, Selank showed immunomodulatory action. This is data on the molecule, not a claim about the research-grade product.
Note: The information is presented for scientific and informational purposes and is based on the literature on Selank. It does not constitute medical advice, a recommendation for use or a claim about the effect of the research-grade product offered by Peptology.
Selank profile at a glance
- Nootropic and anxiolytic peptide (tuftsin derivative) — calms and sharpens at the same time
- Modulates the GABA system as well as serotonin and dopamine
- Acts immunomodulatorily — linking the neural and immune axes
- Heptapeptide — Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Nootropic pair with Semax — often studied together
- Every batch with a CoA and confirmed laboratory purity
All information provided refers to the research literature on Selank and should not be interpreted as a promise of effect, an instruction for use or a claim about the effect of the research-grade product offered by Peptology.
Research dosing protocols
Important: The information below describes schedules used in research on Selank. It is provided for scientific and informational purposes and does not constitute a recommendation for individual use, medical advice or administration instructions. The research-grade Selank offered by Peptology is not a medicinal product.
In research protocols, Selank is administered after reconstitution of the lyophilizate, most often subcutaneously or intranasally:
- Subcutaneous or intranasal administration is described, per the research protocol
- First effects are sometimes observed within a few days
- Calculate precise volumes and units in the peptide calculator (max. 3 mL of solvent per vial)
- In nootropic research often paired with Semax for a synergistic effect
These schedules come from the research literature and do not constitute a recommendation for self-administration.
Side effects and safety
Side effects described in the literature are rare and mild. The data concern research on the molecule.
Data basis
- Mainly Russian studies on the molecule
- Not data on the research-grade product
Rare (mild)
- Irritation at the injection site
- Slight fatigue or drowsiness at the start
Transient
- Headache (usually resolving)
- Hypersensitivity to components
In correctly planned research protocols, no serious side effects are observed. This information is scientific in nature and does not constitute an instruction for use.
Storage and reconstitution
Selank is supplied as a lyophilized (freeze-dried) powder in a vial. In lyophilized form it is stable at room temperature, protected from light and moisture — refrigeration before reconstitution is not mandatory. After reconstitution, stability depends on the solvent used, with Peptide Matrix Water™ significantly extending the peptide's lifespan.
- Before reconstitution: room temperature, in the original packaging, protected from light and moisture. A refrigerator is not mandatory.
- After reconstitution with Peptide Matrix Water™: stability in the refrigerator +2 °C to +8 °C for up to 60 days under appropriate laboratory conditions — the stabilizing formula extends the peptide's lifespan relative to standard solvents.
- Freezing: not recommended — freeze/thaw cycles degrade the peptide structure.
- Reconstitution: in a laboratory setting, Peptide Matrix Water™ is usually used, added slowly down the vial wall, without shaking.
- Volume: maximum 3 mL of solvent (capacity of a standard vial). For a precise calculation of volume and units, use the peptide calculator.
- Homogenization: after adding the solvent, wait 10–15 min, gently rolling the vial between your hands. Do not shake.
Laboratory tip: With your order, you can add Peptide Matrix Water™ to the cart — a stabilizing solution designed for working with reconstituted research peptides. More in the article Bacteriostatic water vs acetic acid vs matrix water.
Frequently asked questions about Selank
What exactly is Selank?
It is a synthetic nootropic and anti-anxiety peptide, a derivative of natural tuftsin. In studies it is associated with the reduction of anxiety, improvement of concentration and memory, and support of immunity. The results come from the research literature.
How fast does Selank work?
In studies, the first effects are usually felt within a few days. This is data on the molecule, not a promise of an effect of the research-grade product.
Is Selank addictive?
The research-grade product has not been studied for this. The literature on the molecule (mainly Russian) compares Selank with classic benzodiazepine anxiolytics; these data concern the molecule, not the product, which is intended exclusively for laboratory research.
Can Selank be combined with other peptides?
In nootropic research, Selank is sometimes combined with Semax for a synergistic effect — Selank calms, Semax activates. This is a combination described in the literature, not a recommendation for use.
How does it differ from Semax?
Both are Russian nootropic peptides, but with a different emphasis. Selank acts primarily anti-anxiety and calming (the GABA system), while Semax is more activating and neuroprotective (BDNF, dopamine).
Where to buy Selank for research?
Peptology offers Selank 5 mg as a research peptide with confirmed purity and independent laboratory analysis for every batch. Fast shipping, discreet packaging and certificates of purity with the product. For scientific background, also see the article Peptides — what they are, how they work, main categories and safety profile.
Related products in the Peptology catalog
Researchers working with Selank often also consider related nootropic and neuroimmune peptides. Each of the products below has a certificate of purity (CoA):
Semax
Nootropic pair — neuroprotection and activation
Thymulin
Neuroimmune regulator (Zn)
Thymosin Alpha-1
Thymic peptide — immunostimulator
KPV
Anti-inflammatory peptide — immunity and gut
Kisspeptin-10
Regulator of the hormonal axis (GnRH)
Peptide Matrix Water™
Stabilizing solution for reconstitution
See the full catalog: Peptides for immunity and hormonal balance · Peptides for skin, sleep and libido · All peptides · Blog on peptide research
Research warning: Selank is offered exclusively for scientific research and in vitro purposes. It is not a medicinal product, is not approved for use in humans or animals, and does not replace medical advice. All information comes from the research literature and is provided for scientific and informational purposes; it does not constitute a claim about the effect of the product.
Laboratory reconstitution
Laboratory protocol — reconstitution, research protocols, storage
Standardized protocol applicable to all research peptides in the Peptology catalogue. To calculate the solution concentration (mg/mL) for each vial, use the peptide reconstitution calculator.
60-second protocol
1. SOLVENT
2. RECONSTITUTION
Add the solvent down the side of the vial, without shaking, wait 10–15 min.
3. CALCULATION
Calculator → concentration mg/mL
4. STORAGE
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water
Quick reference
| Parameter | Value |
|---|---|
| Form | Lyophilized powder |
| Solvent | Peptide Matrix Water |
| Reconstitution volume | 1–3 mL — maximum 3 mL (capacity of the standard vial) |
| Storage before reconstitution | Room temperature, protected from direct light (refrigeration not required) |
| After reconstitution | Up to 60 days at +2 °C to +8 °C with Peptide Matrix Water |
What you need
Precision pipette
Calibrated, 100–1000 µL — for accurately measuring the volume of solvent added to the vial.
70% alcohol swabs
Two swabs — to disinfect the peptide vial and the solvent vial.
Stabilized solvent for lyophilized peptides. Why this one.
Five rules for reconstitution
| ✅ Correct | ❌ Mistake |
|---|---|
| Disinfect the vial caps and the work surface with 70% alcohol; wear gloves | Working without disinfection |
| Add the solvent slowly along the vial wall | Direct jet onto the powder — foaming and denaturation |
| Gentle rolling between the palms | Shaking — foam, which denatures peptides |
| 10–15 minutes waiting at room temperature | Mechanical mixing or heating |
| Visual check: clear, particle-free | Working with a cloudy or discolored solution |
Calculating concentration
⚠️ Maximum 3 mL solvent. The standard vial does not accommodate larger volumes — do not exceed during reconstitution.
- Concentration (mg/mL) = mg in the vial ÷ mL of solvent
- Volume per sample (mL) = amount per sample (mg) ÷ concentration (mg/mL)
- 1 mg/mL = 1 µg/µL · 1 mL = 1000 µL
Reconstitution per vial — solvent: Peptide Matrix Water. Concentration after adding the solvent (1 mg/mL = 1 µg/µL):
| Vial | + 1 mL | + 2 mL | + 3 mL |
|---|---|---|---|
| 5 mg | 5 mg/mL | 2.5 mg/mL | 1.67 mg/mL |
| 10 mg | 10 mg/mL | 5 mg/mL | 3.33 mg/mL |
👉 For any vial and solvent volume — use the calculator. It calculates the concentration (mg/mL, µg/µL) and the volume per sample (mL, µL).
Storage
BEFORE RECONSTITUTION
Room temperature, protected from direct light, in original packaging. Refrigerator not required.
AFTER RECONSTITUTION
+2 °C to +8 °C, up to 60 days with Peptide Matrix Water. Discard any remainder after this period.
FREEZING
Not recommended. Freeze/thaw cycles degrade peptide structure.
Four mistakes to avoid
1. Shaking "to dissolve faster"
Foam = denaturation. Only gentle rolling between the palms.
2. Inappropriate solvent
For peptide stability use only sterile, specially formulated solvent — recommended Peptide Matrix Water.
3. Ignoring slight turbidity
Not fully clear = the sample does not meet the criteria for use.
4. Taking it out of the refrigerator "for an hour–two"
Short exposures add up and compromise stability.
Research status: All Peptology products are intended for laboratory and research use only. They are not medicinal products, not approved for human or veterinary use and do not substitute medical advice. The described protocol is standard laboratory practice for working with lyophilized peptides.
Shipping information
🚚 Shipping information
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Products in our warehouse – orders placed by 15:00 on working days are dispatched the same day, later orders on the next working day.
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Delivery with GLS to your address in 3–5 working days.
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Shipping costs €5 and is free from €50.
Frequently Asked Questions (FAQ)
In what form is Selank supplied and how should it be stored?
It is supplied as a lyophilized (freeze-dried) powder in a sealed vial. Store the unopened vial dry and protected from light, ideally at 2–8 °C. After laboratory reconstitution, keep the solution at 2–8 °C and use it within the period stated in the “Laboratory reconstitution” tab (up to 60 days with Peptide Matrix Water).
What purity does Selank have and how is it tested?
Every batch has a purity of 99% or higher, confirmed by HPLC and mass spectrometry (MS) and documented in a certificate of analysis (CoA). The report for the current batch is shown in the “Laboratory Analysis” tab.
Is a prescription required?
The product is for research use only and does not require a prescription.
Where can I buy Selank in Europe and what does it cost?
You can buy Selank in Europe online from Peptology, from 25,00 €. Delivery with GLS in 3–5 working days. Shipping is free from 50,00 €. Payment by card. Purity 99%+, with an HPLC report for every batch.
Laboratory Analysis
Selank - 5 mg - Batch - 0226 - Purity
Selank - 10 mg - Batch - 0226 - Purity
